Polynucleotide Treatment

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Polynucleotide Treatment Borciani London

At Borciani London, we are thrilled to offer the revolutionary Polynucleotide treatment, an advanced solution for skin rejuvenation that is reshaping the aesthetics industry. This innovative treatment utilises the power of polynucleotides—tiny DNA fragments—to stimulate your skin’s natural ability to repair and regenerate, leading to a more youthful, vibrant appearance.

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What Are Polynucleotides?

They are naturally occurring molecules crucial for cellular repair and regeneration. When used in cosmetic treatments, they act as bio-stimulants, enhancing the skin’s elasticity, hydration, and overall quality. This makes them particularly effective in addressing signs of ageing such as wrinkles, fine lines, and sagging skin.

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Benefits of Polynucleotides

The truly unique thing about these powerful fragments is that they target all signs of ageing, not only the skin. They improve deep dermis and the underlying structure of the face and body to firm, restore and rejuvenate.

  • Enhanced Skin Elasticity: they  boost the production of collagen and elastin, vital proteins that maintain the skin’s firmness and resilience.
  • Deep Hydration: These molecules attract and retain moisture, giving your skin a dewy, refreshed look.
  • Hair Loss: Weakening of the hair bulb, telegen effluvium, androgenetic alopecia, thinning brows and beard
  • Reduction of Dark Circles and Wrinkles: Especially effective for the delicate under-eye area, polynucleotides help minimise shadows and smooth out fine lines.
  • Improved Skin Texture: Regular treatments can significantly enhance skin smoothness and reduce the appearance of wrinkles.
  • Signs of Ageing: wrinkles, fine lines, crepey skin, and sun damage.
  • Acne, Rosacea, Hyperpigmentation, Cell Turnover
biorevitaliser for firmer skin

Treatment Process

Consultation: Our experts will assess your skin and discuss your goals to create a customised treatment plan.

Application: Polynucleotides are injected into the targeted areas using fine needles or a cannula, a process that is minimally invasive and virtually painless.

Aftercare: Post-treatment, our team will provide you with comprehensive aftercare instructions to maximise the benefits and ensure a smooth recovery

The recommended protocols are 3 treatments 2 weeks apart – your practitioner will be able to advise on the best course for you.

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Polynucleotides v Profhilo

What’s the Difference

We are often asked what the difference is between Profhilo and Polynucleotides .  When it comes to skin rejuvenation both of these treatements are a great option.  So, what makes them different, and which one is right for you?

Polynucleotides: Polynucleotides are a newer, cutting-edge treatment that uses DNA fragments to repair and rejuvenate the skin. They help to stimulate collagen, elastin, and improve tissue regeneration. They’re known for their ability to heal damaged skin, brighten, and give a ‘glass skin’ effect.

Best for:

  • Reversing signs of ageing
  • Scarring (including acne scars)
  • Pigmentation and sun damage
  • Tired, sagging skin
  • Skin repair and healing

Benefits:

  • Deep tissue regeneration
  • Evens skin tone
  • Improves texture and skin firmness
  • Strong anti-inflammatory and repair properties

Profhilo: Profhilo is a unique, injectable treatment containing a high concentration of pure hyaluronic acid. Unlike traditional fillers, it spreads beneath the skin to deeply hydrate, improve skin elasticity, and stimulate collagen production.

Best for:

  • Loss of skin elasticity
  • Dehydrated skin
  • Tired, dull-looking skin

Benefits:

  • Ultra-hydrating
  • Boosts collagen and elastin
  • Plumps and firms the skin
  • Improves overall skin quality

Commonly Asked Questions

How many treatments will I need?

This will depend on the area we are treating but most patients will follow the standard protocol which is  2 sessions, 14 days apart from each other, followed by another 1-2 sessions, 21 days apart.

Maintenance can be carried out every 3-6 weeks.

What does the treatment feel like?

The treatment is very comfortable and we will use a topical anaesthetic.  Very small needles are used to inject the product or we can also use microneedling to implant the polynucleotides.

Who is a good candidate?

Anyone looking to improve the quality of their skin naturally without the use of anti wrinkle injections or dermal fillers.

This treatment may not be suitable for:

  • Vegetarians and vegans: Polynucleotides are derived from animal products, such as salmon or trout. 
  • People with fish allergies:
  • People who are pregnant or breastfeeding: Polynucleotides are not recommended during pregnancy or while breastfeeding. 
  • People with active skin infections: Polynucleotides should not be used on people with active skin infections. 
  • People with autoimmune disorders or compromised immune systems: Polynucleotides may not be suitable for people with autoimmune disorders or compromised immune systems. 

What are the costs?

Please check our pricing page for the most up to date costs.

Do I need to prepare for the treatment?

Please try to hydrate before the treatment and avoid retinols for a few days prior.  Do not take any blood thining medications (unless these are prescribed).

How will I look afterwards, is there any downtime?

The downtime is comparable to any injectable and this inlcudes a small chance of bruising.  There may be small bumps visible for 24-48 hours around the eyes although these tend to disperse within a few hours.

What is the aftercare?

Please avoid touching the area that has been treated.  Avoid alcohol and any heat sources such as saunas to prevent bruising.

Get in Touch for a Consultation

If you are unsure of which treatment to choose, please book a consultation to discuss your options or if you prefer to have a treatment at the same time then the Custom Facial is an excellent option – we assess your skin and recommend a treatment plan based on downtime, lifestyle and budget. Or please do get in touch with our practitioners.

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Give us a call or fill in the form below and we will contact you. We endeavor to answer all inquiries within 24 hours on business days.





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    By booking, you agree to our 48-hour notice policy. Please contact us to reschedule or cancel; missed appointments will be charged 100% of the treatment cost.